Work

LKB1 loss links serine metabolism to DNA methylation and tumorigenesis

Year: 2016

Type: article

Source: Nature

DOI: 10.1038/nature20132

Authors: Filippos Kottakis, Brandon N. Nicolay, Ahlima Roumane, Rahul Karnik, Hongcang Gu, Julia M. Nagle, Myriam Boukhali, Michele C. Hayward, Yvonne Y. Li, Ting Chen, Marc Liesa, Peter S. Hammerman, Kwok Kin Wong, D. Neil Hayes, Orian S. Shirihai, Nicholas J. Dyson, Wilhelm Haas, Alexander Meissner, Nabeel Bardeesy

Institutions: Harvard University, Massachusetts General Hospital, Broad Institute, Harvard Stem Cell Institute, University of North Carolina at Chapel Hill, UNC Lineberger Comprehensive Cancer Center, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston University, University of California, Los Angeles

Language: English

Topic: Epigenetics and DNA Methylation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Hirshberg Foundation for Pancreatic Cancer Research, National Institutes of Health, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: TGF-beta Signaling in Pancreatic Cancer, G3492502954, Mitochondrial regulation of energy efficiency, Genetics and Biology of Pancreatic Ductal Adenocarcinoma

OpenAlex ID: W2540090384

FWCI: 12.42

Cites: 68

Cited by: 349

Related to: 10