Year: 2014
Type: article
Study design: Observational Study
Abstract: Adrenal gland is one of metastatic areas of malignant tumours. Adrenal metastasis was identified as between 13-17% in post-mortem autopsy series of metastatic tumours. Adrenal metastasis is mostly observed in the lung and primary renal tumours. However, isolated adrenal metastasis was observed in less than 1% of the cases. Characteristics of the masses in cross-sectional monitoring methods are the best way of showing the difference between benign and malignant adrenal masses. In this retrospective study, we have planned to compare the AI (adrenal incidentaloma) patients with and without malignancy among the cases of AI.Characteristics of the 366 patients, who were detected with AI through MRI or CT found from the retrospective examination of the internal medicine and endocrinology clinic of our hospital records between 2010-2013, were evaluated. In the examination of the adrenal masses sizes of the patients, the largest sized mass of the patients with bilateral adrenal masses was examined. Monitoring characteristics and primary malignancy status were considered when retrospectively distinguishing the AI patients whether benign or malignant.It was detected from the records that 233 of the patients (69.8%) of our study had benign adrenal masses while the remaining 113 patients (30,8%) had metastatic adrenal masses. 220 (60.2%) men and 146 (39.8%) female patients were added to our study. It was observed that 54.9% of the patients with benign adrenal masses and 71.7% of the patients with adrenal metastasis were male (p <0.01). 53 of the patients (46.9%), considered as adrenal metastases, were lung originated while the other frequently seen malignancies were endometrial cancer (9%), breast cancer (5.3%), colon cancer (8.8%), prostate cancer (4.4%) respectively. While unilateral adenoma was detected in 41.5% of the patients admitted with benign adrenal masses, the percentage was found as 20.4% in the cases regarded as adrenal metastasis (p<0.01). On the other hand, bilateral adrenal masses were detected in 25 patients (17.89%). The ratio of the applications with bilateral adrenal masses was found higher in the group of patients with adrenal metastasis (p<0.01).The possibility of adrenal metastasis must be taken into consideration for the admitted patients with adrenal masses. Besides, the adrenal glands must be examined in detail via monitoring methods in primary malignancies cases especially in lung cancer cases. It must be given privilege to the possibility of malignancy for the applications with bilateral adrenal masses.
Source: DergiPark (Istanbul University)
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7012879286