Work

The use of biomarker-based models in clinical settings to support early detection of and treatment for Alzheimer's disease.

Year: 2025

Type: article

Abstract: Traditional detection of and treatment methods for Alzheimer’s disease (AD) undermine the critical period of preclinical AD, a pathogenic process that appears decades before clinical symptoms arise. In the preclinical stage, biomarkers stipulate the advent of pathogenic processes, providing a crucial framework to integrate early detection and intervention well before clinical symptoms become evident. I hypothesize that the presence of biomarkers is a crucial early indicator of changes in memory function in the preclinical stage of AD. To test this hypothesis, a systematic literature review will be applied to gauge biomarker detection in order to consider it as a potential predictive measure in treatment interventions.

Source: ThinkIR: The University of Louisville's Institutional Repository (University of Louisville)

Author: Gonzales, Steven A

Institution: University of Louisville

Language: English

Topic: Dementia and Cognitive Impairment Research

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7015871338

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