Year: 2020
Type: dissertation
Abstract: Treatment and survival of cancer has improved remarkably over the last decades. In particular the advent of targeted therapies, including cell cycle inhibitors, kinase inhibitors and others, have improved outcomes of several types of cancer. However, tumor relapse due to resistance acquisition is often observed and a better understanding of cancer signaling in order to devise novel targeted treatment strategies is thus still required. The aim of this thesis was to further investigate phosphorylation events in different malignancies and determine whether low molecular weight protein tyrosine phosphatase could potentially be a target for treatment.
Author: Sousa Faria, Alessandra
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
Awards: InGrowth, biomimetic product developed by platelet bioactivation platform: applications in the veterinary and research and development areas, G4402799499, G4470102072, Low molecular weight protein tyrosine phosphatase in colorectal cancer: from the bench to product generation, G5902659572, Human platelet lysate: from discard to value products in cell therapy and advanced cell-based medicine
OpenAlex ID: W7018529362