Modern Approaches to the Design and Optimisation of Reactors for Pharmaceutical Manufacturing in the Transition to Continuous Processes and Microgravity Research
Year: 2025
Type: article
Abstract: Different reactor types were examined, including batch reactors whose optimization involved studying equipment design and operating variables—traditionally under the assumption of perfect mixing. To account for non‑idealities in batch reactors, a cell‑model approach was proposed. In continuous processes, plug‑flow (tubular) reactors are widely used, where engineers strive to achieve ideal displacement (plug‑flow) conditions. Separately, biofilm reactors under simulated micro‑gravity were analysed to investigate biofilm growth in spaceflight environments.
Authors: Zipman, R. O., Melnyk, V. M.
Language: English
Topic: Fluid Dynamics and Mixing
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W7020937966
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