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Myelitis and anti-Yo antibodies: a paraneoplastic syndrome associated with nasopharyngeal carcinoma detected by positron emission tomography. A case report

Year: 2024
Type: article
Abstract: SUMMARY: Introduction and objective: Paraneoplastic syndromes (PS) associated with nasopharyngeal carcinoma (NC) are very rare. We described a patient who presented with a paraneoplastic mielitis associated with anti-Yo antibodies and NC. Description: A 70 year-old previously healthy man presented with a progressive gait disorder. The diagnosis work up demonstrated both the presence of anti-Yo antibodies together with a NC, suspected by positron emission tomography (PET-CT). Despite prompt treatment with steroids, gammaglobulins and a satisfactory tumour therapy, partial neurological symptomathology persisted. Conclusions: Although rare, clinicians should consider the possibility of paraneoplastic aetiology when attending patients with NC presenting with subacute neurological symptoms.
Authors: Riancho, Javier, Rodríguez-rodríguez, Eloy, Martínez Camerano, Andrea, Morales Angulo, Carmelo
Language: English
Subfield: Neurology
Field: Medicine
Open Access status: green
OpenAlex ID: W7021152486
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