Isolated hemihyperplasia in an infant: an overlooked sign for wilms tumor development.
Year: 2010
Type: article
Study design: Case Report
Abstract: BACKGROUND: Children with overgrowth syndromes including isolated hemihyperplasia have an increased risk for developing embryonal tumors, particularly Wilms' tumor and hepatoblastoma. Screening with sonography has been suggested as a method of identifying these tumors while they are still at an early stage. CASE PRESENTATION: We describe an infant diagnosed with Wilms tumor in whom isolated hemihyperplasia had been overlooked by several physicians prior to the tumor diagnosis. CONCLUSION: We recommend tumor surveillance for all patients with Beckwith-Wiedemann syndrome and isolated hemihyperplasia at least for the first six years of life since full molecular characterization of every patient is not readily available.
Source: Europe PMC (PubMed Central)
Authors: Kamer Mutafoglu, Emre Cecen, Handan Cakmakci
Institution: Dokuz Eylül University
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2123724346