Work

Utilisation of rapeseed protein isolates for production of peptides with angiotensin I-converting enzyme (ACE)-inhibitory activity

Year: 2004

Type: article

Abstract: ACE activity is related to increased arterial pressure and coronary diseases. A rapeseed protein isolate was hydrolyzed with the protease Alcalase in order to investigate the possible presence of ACE inhibitory peptides in the resulting hydrolysates. Hydrolysis for 30 min yielded a hydrolysate with the highest ACE inhibitory activity. Two fractions of this hydrolysate obtained by Biogel P2 gel filtration chromatography were used for further purification of ACE inhibitory peptides. Three fractions with ACE inhibitory activity were purified by reverse-phase HPLC of Biogel P2 f ractions. This demonstrates that rapeseed protein hydrolysates represent a good source of ACE inhibitory peptides .

Source: Grasas y Aceites

DOI: 10.3989/gya.2004.v55.i4.200

Authors: Justo Pedroche, María M. Yust, Cristina Megías, Hassane Lqari, Manuel Alaiz, Julio Girón-Calle, Francisco Millán, Javier Vioque

Institutions: Consejo Superior de Investigaciones Científicas, Instituto de la Grasa

Language: English

Topic: Protein Hydrolysis and Bioactive Peptides

Subfield: Food Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2088127521

FWCI:

Cites: 25

Cited by: 27

Related to: 10