Serum Micronutrient Status, Sleep Quality and Neurobehavioral Function Among Early Adolescents
Year: 2021
Type: article
Study design: Observational Study
Abstract: Objective: To examine associations between serum micronutrients and neurobehavioral function and the mediating role of sleep quality in early adolescents. Design: In this cross-sectional study, peripheral blood samples were analyzed for iron and zinc levels. The Pittsburgh Sleep Quality Index and Penn Computerized Neurocognitive Battery were used to assess sleep quality and neurobehavioral function, respectively. The generalized linear regressions (bootstrap) were performed to estimate the associations. Setting: Jintan, China Participants: 226 adolescents (106 females) from the Jintan Child Cohort study. Results: Adolescents with low iron (< 75 ug/dl) (OR=1.29, p=0.04) and low zinc (< 70 ug/dl) (OR=1.58, p0.05). Conclusion: Iron and zinc deficiencies may possibly be associated with poor sleep and neurobehavioral function among early adolescents. Poor sleep may partially mediate the relationship between micronutrients and neurobehavioral function.
Authors: Ji, Xiaopeng, Compher, Charlene W., Irving, Sharon Y., Kim, Jinyoung, Dinges, David F., Liu, Jianghong
Language: English
Topic: Trace Elements in Health
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Open Access status: green
Awards: Environmental Toxicity, Malnutrition, and Children's Externalizing Behavior, Mechanisms that mediate the link between lead exposure and child behavior problem, G842207449, Lead exposure, externalizing behavior, and neurobiological mediating factors, Center of Excellence in Environmental Toxicology
OpenAlex ID: W7043183222