Sarcopenia em idosos sedentários e sua relação com funcionalidade e marcadores inflamatórios (IL-6 e IL-10)
Year: 2016
Type: article
Study design: Observational Study
Abstract: INTRODUCTION: Sarcopenia is progressive loss of skeletal muscle mass related to aging. A sedentary lifestyle is a major factor related to the imbalance between synthesis and protein degradation, especially in the elderly. OBJECTIVE: To investigate the prevalence of sarcopenia in a group of sedentary elderly and its relationship to physical strength and inflammatory markers. METHODS: were conducted in 53 elderly collection of anthropometric data, assessment of body composition, functional test (Timed Up and Go), test of strength (grip) and collecting blood sample for evaluation of inflammatory markers. RESULTS: The prevalence of sarcopenia in the sample was 50% men and 54% among women. The average age was 71.3 years old in sarcopenia group and 66.4 years in non sarcopenia group (p = 0.015). There was no statistically significant difference between the values found for IL-6 (p = 0.70) and IL-10 (p = 0.14). CONCLUSION: There was a high prevalence of sarcopenia in sedentary elderly and muscle mass loss was associated with loss of muscle strength in men and women. There was no association with inflammatory markers IL-6 and IL-10.
Source: Geriatrics Gerontology and Aging
Authors: Universidade Católica de Brasília, Gisele Soares Mendes, Thaís Helena Machado Marçal Teixeira, Fundação de Ensino e Pesquisa em Ciências da Saúde, Vinicius Carolino de Souza, Universidade Católica de Brasília, Universidade de Brasília, Tiago Sousa Neiva, Universidade Católica de Brasília, Secretaria do Estado de Saúde do Distrito Federal, Karina Prudente Pereira, Secretaria do Estado de Saúde do Distrito Federal, Maria de Fátima Teles Landim, Universidade Católica de Brasília, Gislane Ferreira de Melo, Universidade Católica de Brasília, Juliana de Faria Fracon e Romão, Universidade de Brasília, Otávio Tolêdo Nóbrega, Universidade de Brasília, Gustavo de Azevedo Carvalho, Universidade Católica de Brasília
Language: Portuguese
Subfield: Physiology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2471804362