Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Year: 2016
Type: article
Study design: Observational Study
Source: Nature Genetics
DOI: 10.1038/ng.3725
Authors: Christian R. Marshall, Daniel P. Howrigan, Daniele Merico, Bhooma Thiruvahindrapuram, Wenting Wu, Douglas S. Greer, Danny Antaki, Aniket Shetty, Peter A. Holmans, Dalila Pinto, Madhusudan Gujral, William M. Brandler, Dheeraj Malhotra, Zhouzhi Wang, Karin V. Fuentes Fajarado, Stephan Ripke, Ingrid Agartz, Esben Agerbo, Margot Albus, Madeline Alexander, Farooq Amin, Joshua Atkins, Silviu A. Bacanu, Richard A. Belliveau, Sarah E. Bergen, Marcelo Bertalan, Elizabeth Bevilacqua, Tim B. Bigdeli, Donald W. Black, Richard Bruggeman, Nancy G. Buccola, Randy L. Buckner, Brendan Bulik-Sullivan, William Byerley, Wiepke Cahn, Guiqing Cai, Murray J. Cairns, Dominique Campion, Rita M. Cantor, Vaughan J. Carr, Noa Carrera, Stanley V. Catts, Kimberley D. Chambert, Wei Cheng, C. Robert Cloninger, David Cohen, Paul Cormican, Nick Craddock, Benedicto Crespo-Facorro, James J. Crowley, David Curtis, Michael Davidson, Kenneth L Davis, Franziska Degenhardt, Jurgen Del Favero, Lynn E. DeLisi, Ditte Demontis, Dimitris Dikeos, Timothy Dinan, Srdjan Djurovic, Gary Donohoe, Elodie Drapeau, Jubao Duan, Frank Dudbridge, Peter Eichhammer, Johan Eriksson, Valentina Escott-Price, Laurent Essioux, Ayman H. Fanous, Kai-How Farh, Martilias S. Farrell, Josef Frank, Lude Franke, Robert Freedman, Nelson B. Freimer, Joseph I. Friedman, Andreas J. Forstner, Menachem Fromer, Giulio Genovese, Lyudmila Georgieva, Elliot S. Gershon, Ina Giegling, Paola Giusti-Rodríguez, Stephanie Godard, Jacqueline I. Goldstein, Jacob Gratten, Lieuwe de Haan, Marian L. Hamshere, Mark Hansen, Thomas Hansen, Vahram Haroutunian, Annette M. Hartmann, Frans A. Henskens, Stefan Herms, Joel N. Hirschhorn, Per Hoffmann, Andrea Hofman, Mads V. Hollegaard, David M. Hougaard, Hailiang Huang, Masashi Ikeda, Inge Joa, K Kähler Anna, René S Kahn, Luba Kalaydjieva, Juha Karjalainen, David Kavanagh, Matthew C. Keller, Brian J. Kelly, James L. Kennedy, Yunjung Kim, James A. Knowles, Bettina Konte, Claudine Laurent, Phil Lee, S. Hong Lee, Sophie E. Legge, Bernard Lerer, Deborah L. Levy, Kung-Yee Liang, Jeffrey Lieberman, Jouko Lönnqvist, Carmel M. Loughland, Patrik K.E. Magnusson, Brion S. Maher, Wolfgang Maier, Jacques Mallet, Manuel Mattheisen, Morten Mattingsdal, Robert W McCarley, Colm McDonald, Andrew M. McIntosh, Sandra Meier, Carin J. Meijer, Ingrid Melle, Raquelle I. Mesholam-Gately, Andres Metspalu, Patricia T. Michie, Lili Milani, Vihra Milanova, Younes Mokrab, Derek W. Morris, Ole Mors, Bertram Müller-Myhsok, Kieran C. Murphy, Robin M. Murray, Inez Myin-Germeys, Igor Nenadic, Deborah A. Nertney, Gerald Nestadt, Kristin K. Nicodemus, Laura Nisenbaum, Annelie Nordin, Eadbhard O’ Callaghan, Colm O’ Dushlaine, Sang-Yun Oh, Ann Olincy, Line Olsen, F. Anthony O’ Neill, Jim Van Os, Christos Pantelis, George N. Papadimitriou, Elena Parkhomenko, Michele T. Pato, Tiina Paunio, Diana O. Perkins, Tune H. Pers, Olli Pietiläinen, Jonathan Pimm, Andrew J. Pocklington, John Powell, Alkes Price, Ann E. Pulver, Shaun M. Purcell, Digby Quested, Henrik B. Rasmussen, Abraham Reichenberg, Mark A. Reimers, Alexander L. Richards, Joshua L. Roffman, Panos Roussos, Douglas M. Ruderfer, Veikko Salomaa, Alan R. Sanders, Adam Savitz, Ulrich Schall, Thomas G. Schulze, Sibylle G. Schwab, Edward M. Scolnick, Rodney J. Scott, Larry J. Seidman, Jianxin Shi, Jeremy M. Silverman, Jordan W. Smoller, Erik Söderman, Chris C.A. Spencer, Eli A. Stahl, Eric Strengman, Jana Strohmaier, T. Scott Stroup, Jaana Suvisaari, Dragan M. Svrakic, Jin P. Szatkiewicz, Srinivas Thirumalai, Paul A. Tooney, Juha Veijola, Peter M. Visscher, John Waddington, Dermot Walsh, Bradley T. Webb, Mark Weiser, Dieter B. Wildenauer, Nigel M. Williams, Stephanie Williams, Stephanie H. Witt, Aaron R. Wolen, Brandon K. Wormley, Naomi R Wray, Jing Qin Wu, Clement C. Zai, Rolf Adolfsson, Ole A. Andreassen, Douglas H.R. Blackwood, Anders D. Børglum, Elvira Bramon, Joseph D. Buxbaum, Sven Cichon, David A. Collier, Aiden Corvin, Mark J. Daly, Ariel Darvasi, Enrico Domenici, Tõnu Esko, Pablo V. Gejman, Michael Gill, Hugh Gurling, Christina M. Hultman, Nakao Iwata, Assen V. Jablensky, Erik G Jönsson, Kenneth S Kendler, George Kirov, Jo Knight, Douglas F. Levinson, Qingqin S Li, Steven A McCarroll, Andrew McQuillin, Jennifer L. Moran, Preben B. Mortensen, Bryan J. Mowry, Markus M. Nöthen, Roel A. Ophoff, Michael J. Owen, Aarno Palotie, Carlos N. Pato, Tracey L. Petryshen, Danielle Posthuma, Marcella Rietschel, Brien P. Riley, Dan Rujescu, Pamela Sklar, David St. Clair, James T.R. Walters, Thomas Werge, Patrick F. Sullivan, Michael C O’Donovan, Stephen W. Scherer, Benjamin M. Neale, Jonathan Sebat
Institutions: Hospital for Sick Children, Centre for Applied Genomics, Broad Institute, Massachusetts General Hospital, Stanley Center for Psychiatric Research, University of California San Diego, Cardiff University, Icahn School of Medicine at Mount Sinai, F. Hoffmann-La Roche AG, University of Oslo, Karolinska Institutet, Diakonhjemmet Hospital, Aarhus University, Lundbeck Foundation, Division Technique de I'INSU, Stanford Medicine, Stanford University, Emory University, Atlanta VA Medical Center, Hunter Medical Research Institute, University of Newcastle Australia, Virginia Commonwealth University, Virginia Commonwealth University Medical Center, Mental Health Services, University of Iowa, University Medical Center Groningen, University of Groningen, Louisiana State University Health Sciences Center New Orleans, Harvard University, Athinoula A. Martinos Center for Biomedical Imaging, University of California, San Francisco, University Medical Center Utrecht, Schizophrenia Research Institute, Inserm, Centre Hospitalier du Rouvray, University of California, Los Angeles, UNSW Sydney, The University of Queensland, Royal Brisbane and Women's Hospital, University of North Carolina at Chapel Hill, Washington University in St. Louis, Assistance Publique – Hôpitaux de Paris, Institut Systèmes Intelligents et de Robotique, Université Pierre-et-Marie-Curie, Trinity College Dublin, Universidad de Cantabria, Centro de Investigación Biomédica en Red de Salud Mental, Marqués de Valdecilla University Hospital, Centro de Investigación Biomédica en Red, Queen Mary University of London, University College London, Sheba Medical Center, University of Bonn, Life & Brain (Germany), University of Antwerp, VA Boston Healthcare System, National and Kapodistrian University of Athens, University College Cork, Oslo University Hospital, Ollscoil na Gaillimhe – University of Galway, Endeavor Health, University of Chicago, London School of Hygiene & Tropical Medicine, University of Regensburg, University of Helsinki, Helsinki University Hospital, Finnish Institute for Health and Welfare, Folkhälsans Forskningscentrum, University of Southern California, Georgetown University, Washington DC VA Medical Center, Heidelberg University, Central Institute of Mental Health, Medizinische Fakultät Mannheim, University of Colorado Denver, Martin Luther University Halle-Wittenberg, Ludwig-Maximilians-Universität München, Institut de Myologie, Pitié-Salpêtrière Hospital, Amsterdam UMC Location University of Amsterdam, University of Amsterdam, Illumina (United States), James J. Peters VA Medical Center, University of Basel, Boston Children's Hospital, Statens Serum Institut, Fujita Health University, Stavanger University Hospital, The University of Western Australia, University of Colorado Boulder, Centre for Addiction and Mental Health, University of Toronto, Campbell Family Mental Health Research Institute, Hadassah Medical Center, McLean Hospital, Johns Hopkins University, Columbia University, Centre National de la Recherche Scientifique, Laboratoire de Génétique Moléculaire de la Neurotransmission et des Processus Neurodégénératifs, Sørlandet Sykehus, University of Edinburgh, Beth Israel Deaconess Medical Center, Massachusetts Mental Health Center, University of Tartu, Medical University of Sofia, Eli Lilly (United Kingdom), University of Liverpool, Munich Cluster for Systems Neurology, Max Planck Institute of Psychiatry, Royal College of Surgeons in Ireland, King's College London, Maastricht University Medical Centre, Aarhus University Hospital, European Graduate School of Neuroscience, Jena University Hospital, Queensland Centre for Mental Health Research, Johns Hopkins Medicine, Eli Lilly (United States), Umeå University, Lawrence Berkeley National Laboratory, University of California, Berkeley, Queen's University Belfast, The University of Melbourne, Melbourne Health, Technical University of Denmark, Institute for Molecular Medicine Finland, University of Oxford, Janssen Research & Development (United States), University of Göttingen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsklinikum Erlangen, Hunter New England Local Health District, National Cancer Institute, Division of Cancer Epidemiology and Genetics, Veterans Health Administration, Centre for Human Genetics, Berkshire Healthcare NHS Foundation Trust, Oulu University Hospital, University of Oulu, Health Research Board, Forschungszentrum Jülich, Hebrew University of Jerusalem, University of Trento, Erasmus MC, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC Location Vrije Universiteit Amsterdam, University of Aberdeen, University of Copenhagen
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: bronze
Funders: U.S. Department of Veterans Affairs, Massachusetts General Hospital, Strategiske Forskningsråd, Aarhus Universitet, Højteknologifonden, NHS Blood and Transplant, National Alliance for Research on Schizophrenia and Depression, Wellcome Trust, Pratt Foundation, Max-Planck-Förderstiftung, National Institute for Health and Care Research, European Commission, Deutsche Forschungsgemeinschaft, ZonMw, Vrije Universiteit Amsterdam, Bundesministerium für Bildung und Forschung, Lundbeckfonden, Karolinska Institutet, Max-Planck-Gesellschaft, Alfried Krupp von Bohlen und Halbach-Stiftung, Norges Forskningsråd, H. Lundbeck A/S, Ramsay Health Care, Australian Schizophrenia Research Bank, National Institutes of Health, Seventh Framework Programme, Stanley Center for Psychiatric Research, Broad Institute, Medical Research Council, National Health and Medical Research Council, Strategic Research Council, National Institute of Mental Health, National Human Genome Research Institute, National Center for Research Resources
Awards: 2/7 Psychiatric Genomics Consortium: Finding Actionable Variation, 5/7 Psychiatric Genomics Consortium: Finding actionable variation, UK Dementias Platform, 3/4-Psychiatric GWAS Consortium: Genomic Follow-Up Next-Gen Sequencing & Genotypi, 1/2 A Large-Scale Schizophrenia Association Study in Sweden, G214445032, 1/7 Psychiatric Genomics Consortium: Finding actionable variation, Structural and functional fronto-hippocampal maturation and neurodevelopmental outcome following very preterm birth in adulthood, NIHR Senior Investigator Award, Molecular Genetic Studies of Schizophrenia, 3/7 Psychiatric Genomics Consortium: Finding actionable variation, 1/4 Psychiatric GWAS Consortium: Genomic Follow-up Next-Gen Seq & Genotyping, 4/7 Psychiatric Genomics Consortium: Finding actionable variation, MRC Centre for Neuropsychiatric Genetics and Genomics, Genomic Psychiatry Cohort, G6720140889, Improving Physical Health and Decreasing Cannabis Abuse in People With Severe Mental Illness, Methylomic profiling in schizophrenia: towards an integrated genetic-epigenetic approach, 2/2 Large-Scale Genetic Studies of Schizophrenia in Sweden, G8602010195
OpenAlex ID: W2551102722