Year: 2024
Type: article
Abstract: The article describes a case of successfully reversing folate metabolism disorders in a patient with genetic mutations in the folate cycle genes MTHFR and MTRR, and multiple developmental defects in fetuses (spina bifida) during their history. Folate deficiency increases the risk of pregnancy complications, miscarriage and fetal malformations. The use of standard folic acid dosages proved ineffective, and the fetus developed spina bifida. The formation of developmental defects in the fetus was prevented by increasing the recommended dosage of folic acid.
Source: Matʹ i ditâ v Kuzbasse
Authors: Эльвира Константиновна Гребенникова, Сергей Васильевич Гребенников, Марина Яковлевна Домрачева, Татьяна Алексеевна Соколова-Попова, Наталья Михайловна Яметова, Ольга Александровна Домрачева, Анна Сергеевна Вишневская
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $19
OpenAlex ID: W7053379034
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