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Metformin Therapy and Diabetes Prevention in Adolescents Who Are Obese

Year: 2007

Type: article

Abstract: No studies have addressed the question of whether metformin reduces development of diabetes among adolescents who are obese. Metformin treatment in adolescents who are obese can modestly reduce risk factors for type 2 diabetes, including elevated body mass index (BMI), fasting insulin levels, and fasting glucose levels. (Strength of Recommendation [SOR]: C). However, metformin treatment is associated with nausea, abdominal pain, and diarrhea. (SOR: A). Because of the limited available data, metformin is not recommended for diabetes prevention in adolescents. (SOR: C).

Source: MOspace Institutional Repository (University of Missouri)

Authors: Rodriguez, Jose E., Shearer, Barbara

Language: English

Topic: Diabetes Treatment and Management

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7067661777

FWCI:

Cites:

Cited by: 1

Related to: 10