Ultrasonography for the assessment of contractile properties of fresh and fatigued diaphragm muscle in healthy humans
Year: 2021
Type: dissertation
Abstract: Contractile function of the diaphragm is characterised by its ability to shorten, generate force, produce power and perform work.Due to the diaphragm's inaccessibility, these attributes are typically measured as the pressure difference across the diaphragm in response to twitch stimulation of phrenic nerves (i.e., twitch transdiaphragmatic pressure [∆Pdi,tw]).This technique, however, provides limited information concerning the muscle's ability to shorten under load and to produce power.The overarching aim of this thesis was to determine whether ultrasound imaging could be used to elucidate the in vivo contractile properties of fresh and fatigued diaphragm muscle in healthy humans.Chapter 4 and 5 evaluated the feasibility, validity and intra-observer reliability of ultrasound-derived measures of crural diaphragm excursion, excursion velocity and power (i.e., kinetics) and costal diaphragm shortening in response to nerve
Author: Illidi, Camilla Rønn
Institution: Brunel University of London
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7071699025