Year: 2024
Type: article
Abstract: The study investigates the possibility of diagnosing lung cancer through the simultaneous detection of six tumor biomarkers of this disease (CYFRA21-1, EpCAM, PLAUR, LIFR, ProGRP, and CEA) in blood plasma. The levels of these proteins in blood plasma were determined using square-wave voltammetry with multiplexed electrochemical chips modified with DNA aptamers. The results obtained in the study demonstrated the capability of the multiplex electrochemical aptasensor to simultaneously detect in blood plasma such traditionally used lung cancer tumor markers as CYFRA21-1, EpCAM, PLAUR, LIFR, ProGRP, and CEA
Authors: Glazyrin, Yuri E., Zamay, Galina S., Kichkailo, Anna S., Zamay, Tatiana N., Pats, Yuri S., Zamay, Sergei S., Lukyanenko, Kirill A., Kolovskaya, Olga S., Глазырин, Юрий Е., Замай, Галина С., Кичкайло, Анна С., Замай, Татьяна Н., Пац, Юрий С., Замай, Сергей С., Лукьяненко, Кирилл А., Коловская, Ольга С.
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7072559138
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