Work

Pre-exposure Prophylaxis Use and Medication Adherence Among Men Who Have Sex With Men

Year: 2019

Type: review

Abstract: The appropriate use of pre-exposure prophylaxis (PrEP) by men who have sex with men (MSM) can be highly effective at reducing HIV transmission. Our review examined prevalence estimates, sexual behaviors, and medication adherence among MSM PrEP users in high-income countries. Articles published between January 2008 and December 2018 were identified through Medline, Web of Science, CINAHL, and CENTRAL. The search identified 643 publications, of which 52 were included in the final synthesis. We found that PrEP initiation was not consistently associated with significant changes in sexual behavior, but some users may have risk compensated. A minority of MSM used PrEP, and they had high levels of adherence. PrEP-related stigma, side effects, and psychosocial factors lead to nonadherence. A daily routine, pill boxes, alarms/texts, and education can promote adherence. Further research is required to examine PrEP impact on sexual behavior and factors that influence adherence in high-risk MSM subpopulations.

Source: Journal of the Association of Nurses in AIDS Care

DOI: 10.1097/jnc.0000000000000105

Authors: Steven Maxwell, Mitzy Gafos, Maryam Shahmanesh

Institutions: London School of Hygiene & Tropical Medicine, University College London, University of Edinburgh

Language: English

Topic: HIV/AIDS Research and Interventions

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2952231760

FWCI: 0.919

Cites: 69

Cited by: 50

Related to: 10