Year: 2025
Type: article
Abstract: A 61-year-old woman who had been taking olmesartan for 7 years complained of epigastric pain, diarrhea, loss of appetite, and weight loss. Esophagogastroduodenoscopy revealed roughened mucosa and erosions in the stomach and duodenum. An endoscopic biopsy failed to identify the cause of the mucosal disorder. Small-bowel capsule endoscopy revealed villous atrophy in the small bowel, which led to suspicion of olmesartan-associated sprue-like enteropathy and gastritis. After the discontinuation of olmesartan, the symptoms and gastric mucosal findings improved. A final diagnosis of olmesartan-associated gastritis was confirmed. Olmesartan-associated gastritis should be considered in patients taking olmesartan for upper gastrointestinal symptoms.
Authors: Fujisawa, Mizuho, Yoshizaki, Tetsuya, 吉﨑, 哲也, ヨシザキ, テツヤ, Urakami, Satoshi, Ashizaki, Risa, Nishikawa, Eri, Tanabe, Hiroshi, Hoki, Shinya, Ishida, Ryosuke, Hori, Hitomi, Ueda, Chise, Abe, Hirofumi, 阿部, 洋文, アベ, ヒロフミ, Takao, Madoka, 鷹尾, まど佳, タカオ, マドカ, Morita, Yoshinori, 森田, 圭紀, モリタ, ヨシノリ, Toyonaga, Takashi, 豊永, 高史, トヨナガ, タカシ, Kodama, Yuzo, 児玉, 裕三, コダマ, ユウゾウ
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7075634441
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