A Review Article on Nanocarrier-based Drug Delivery Systems: Advances and Challenges
Year: 2025
Type: article
Abstract: Nanocarrier-based drug delivery systems have revolutionized the field of targeted therapy by improving drug solubility, bioavailability, pharmacokinetics, and tissue specificity. This review explores various classes of nanocarriers, including lipid-based, polymeric, inorganic, and exosome-derived systems, and discusses key advances, such as stimuli-responsive drug release and active/passive targeting. Despite these advances, challenges remain in formulation stability, clinical translation, toxicity profiling, and large-scale manufacturing. Future perspectives, such as the incorporation of artificial intelligence (AI) and the design of smart programmable nanocarriers, hold promise for bridging the gap between research and clinical applications.
Authors: Dr. K. Chandra Rekha*, Dr. Y. B. Nagamani
Institution: Government of Andhra Pradesh
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W7075859995
FWCI:
Cites:
Cited by:
Related to: