Work

Therapeutic Use of Mesenchymal Stem Cells May Be a Means of Transmitting Leishmaniasis in Dogs

Year: 2025

Type: article

Abstract: The aim of this case report is to record the finding of leishmaniasis-causing parasites in mesenchymal stem cells from dogs from a non-endemic area, which were negative when submitted to the RIFI and ELISA tests, a fact that had not been documented until now. This demonstrates that this widely distributed and lethal zoonosis can escape traditional means of diagnosis and that stem cell therapy has the potential to be a source of transmission of the disease. Although the relative safety of stem cell therapy is presumed, the possible risks associated with its use, especially the risk of parasite transmission, cannot be ignored. It is therefore essential to develop rigorous screening and testing protocols to ensure the safety of stem cell therapy.

Source: Aracê.

DOI: 10.56238/arev7n2-302

Authors: Vitor Pegorer Bilharinho, Malú Mateus Santos Obata, Joely Ferreira Figueiredo Bittar, Isabel Rodrigues Rosado, Rogéria Serakides, Endrigo Gabellini Leonel Alves

Institutions: Universidade de Uberaba, Universidade Federal de Minas Gerais

Language: English

Topic: Research on Leishmaniasis Studies

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: Universidade Federal de Minas Gerais