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Supplementary Material "Dual anti-inflammatory activity of Trichilia emarginata and insights from UPLC-HRMS chemical profiling annotation"

Year: 2025

Type: supplementary-materials

Abstract: Supplementary MaterialThe chemical profile of T. emarginata leaves in the ESI– mode revealed three main classes of metabolites: caffeoylquinic acid derivatives (mono- and dicaffeoylquinic acids), simple phenolic acids and coumarin-related structures, and highly oxygenated triterpenoids/limonoids together with fatty acid methyl esters. Phenolic acids and chlorogenic derivatives predominated in hydroalcoholic fractions (HAL, CE), while limonoids, sesquiterpenes, and other terpenes were concentrated in non-polar fractions (CHLO, ACT). These compounds are chemotaxonomic markers of the Meliaceae family and have been linked to antioxidant, anti-inflammatory, cytotoxic, and insecticidal activities.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.16923491

Authors: Rafaela, de Lima Moreira, Albert, Katchborian-neto, Miller, Santos Ferreira, Mario, Ferreira Conceição do Santos, Danielle, F. Dias, Daniela, A. Chagas-Paula, Marisi, Gomes Soares

Institutions: Universidade Federal de Alfenas, Universidade Federal do ABC, Universidade Federal do Espírito Santo

Language: English

Topic: Phytochemical compounds biological activities

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W7077141707

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