Year: 2019
Type: dissertation
Abstract: "Lentiviral vectors (LV) are excellent gene transfer tools enabling the transduction of proliferative and non-proliferative cells and the long-term transgene expression. However, LV manufacture is a high cost process characterized by low transducing competent particles yields. This work aimed to address these challenges by 1) enhancing LV transduction efficiencies, and by 2) assisting the development of constitutive LV producer cell lines for continuous, reproducible, and low-cost LV manufacture(...)"
Author: Thome Cabral, Elisa
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
Funder: Svenska Forskningsrådet Formas
OpenAlex ID: W7077577402