Therapeutic Effects of Photobiomodulation and Electrical Stimulation on Xerostomia: A Recent Evidence-Based Review
Year: 2025
Type: article
Abstract: Objective: This study compared and analyzed the effectiveness of recent interventions for xerostomia, including photobiomodulation (PBM), electrical stimulation, and pharmacotherapy. Methods: A systematic review of clinical trials and randomized controlled trials (RCTs) published between 2023 and 2025 was conducted, summarizing protocols (wavelength, session number, treatment duration) and clinical outcomes (symptom improvement rate, changes in salivary flow). Results: PBM and electrical stimulation were highly safe and demonstrated significant improvements in salivary flow and symptom relief, whereas pharmacotherapy showed the greatest overall improvement. These findings provide a foundation for patient-tailored treatment strategies. Conclusion: Etiology-specific customization and multimodal combination therapy are key, with protocol standardization and accumulation of long-term evidence critical for clinical guideline advancement.
Author: Hee Ja NA1 , Ae eun Moon2
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7078756761
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