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Management of Cardiac Amyloidosis: A Narrative Review

Year: 2025

Type: review

Abstract: Amyloidosis is a multi-system disorder in which cardiac involvement often manifests with heart failure and/or arrhythmias. Recognition of cardiac amyloidosis is important as it is a potentially treatable cause of cardiomyopathy. While the approach to a case of suspected cardiac amyloidosis was discussed in a prior article, this one focuses on the management of its two main types (AL and ATTR). This is an area of active research with the advent of newer therapies such as RNA silencers and gene editing. We shall also discuss the management of heart failure and arrhythmias specific to amyloidosis.

Source: Journal of the Practice of Cardiovascular Sciences

DOI: 10.4103/jpcs.jpcs_39_25

Authors: Neha Chopra, Rishi Dhawan, Sandeep Seth

Institutions: Safdarjang Hospital, Vardhman Mahavir Medical College & Safdarjung Hospital, All India Institute of Medical Sciences

Language: English

Topic: Amyloidosis: Diagnosis, Treatment, Outcomes

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7080126242

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Cites: 51

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