The Uniqueness of Albumin as A Carrier in Nanodrug Delivery
Year: 2025
Type: article
Abstract: In nanomedicine, albumin is a highly preferred carrier due to its unique features. It is the most common protein in blood plasma, making it highly compatible with the body, easy to break down, safe, and unlikely to trigger immune responses, which is important for medical use. Its structure allows it to interact with various drugs, potentially protecting them from being removed or broken down in the body, which improves how these drugs work in the body. Another key feature is that albumin can target specific areas of disease because many diseased tissues and cells have an excess of certain receptors. Among nanocarriers, albumin stands out as a highly biocompatible and effective delivery system. It naturally circulates in the body for a long time and doesn't need extra chemical groups to function. This makes it well-suited for personalized medicine because it can specifically target diseased tissues. Drugs that are not easily dissolved in water can be effectively mixed with albumin, increasing their effectiveness and expanding treatment options. Albumin-based nanocarriers have the potential to revolutionize personalized healthcare by delivering precise and effective treatments. However, challenges remain in improving how much medicine can be loaded and ensuring precise targeting.
Author: Vedant Chimote*, Vidya Karhale, Amol Sawale
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W7081645822
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