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Antioxidant Activity of Safflower Oil in Toxic Hepatitis

Year: 2025

Type: article

Abstract: Toxic hepatitis represents a pressing issue in hepatology due to hepatocyte damage caused by chemical and drug intoxication. A critical mechanism of this pathology is oxidative stress, accompanied by lipid peroxidation and a decrease in endogenous antioxidant defense [2, 3]. Natural hepatoprotective agents with antioxidant properties are highly relevant because existing pharmacological therapies often have side effects. Safflower oil, rich in polyunsaturated fatty acids and bioactive compounds, is considered a promising candidate for correcting oxidative imbalance [1, 4]. However, experimental data regarding its efficiency in toxic hepatitis remain limited. Studying its effect on antioxidant parameters is essential for substantiating its clinical potential [5, 6].

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.17118515

Authors: Faizullaeva, N.Ya., Kayumov, A.A., Raufov, A.A.

Language: English

Topic: Drug-Induced Hepatotoxicity and Protection

Subfield: Pharmacology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7081691256

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