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T-cell receptor specificity landscape revealed through de novo peptide design.

PubMed

Year: 2025
Type: preprint
Source: PubMed
Authors: Gian Marco Visani, Michael N Pun, Anastasia A Minervina, Philip Bradley, Paul Thomas, Armita Nourmohammad
Institutions: University of Washington, St. Jude Children's Research Hospital, Fred Hutch Cancer Center
Language: English

Topic: vaccines and immunoinformatics approaches
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Institute of Allergy and Infectious Diseases
Awards: Decoding the interactions between T cell receptors and peptide-MHC, Learning a molecular shape space for the adaptive immune system, Molecular modeling and machine learning for protein structures and interactions
OpenAlex ID: W7081695231
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