Community-acquired Pseudomonas aeruginosa meningitis − A rare case presentation
Year: 2025
Type: article
Abstract: • Importance of early assessment in patients presenting with fever and confusion. • Prompt appropriate investigations, such as lumbar puncture and cultures to isolate causative organisms. • Initiation of targeted antibiotics (based on sensitivities) with blood–brain barrier permeability in those with meningitis. • Early re-assessment to monitor declining inflammatory markers within 48h of treatment initiation in such cases. • Multi-disciplinary team work to identify and manage uncommon aetiologies such as pseudomonas meningitis. Gram-negative bacterial meningitis has a high mortality rate. We present a case of community acquired bacterial meningitis caused by Pseudomonas aeruginosa with a successful outcome following prolonged intravenous antibiotics. Pseudomonas aeruginosa is an uncommon Gram-negative bacterial cause of meningitis. In its rarity, it has no well-established optimal antibiotic therapy (2) . Patients with the above face a severe clinical picture − of the etiological agents, Gram-negative bacilli have the highest fatality rate; 54%. (3) Therefore, the occurrence of Pseudomonas aeruginosa meningitis in the absence of predisposing factors is both an exceptionally rare, and dangerous, finding (3) – here, we describe such a case.
Source: Clinical Infection in Practice
Authors: Sara Hamid, Krishna Girotra, Timothy Kemp, Sajeed Mohammed Abdul, Jooly Joseph, Krishna Banavathi
Institutions: Royal Stoke University Hospital, Keele University
Language: English
Subfield: Microbiology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,000
OpenAlex ID: W7081959974