Therapeutic VEGFC treatment provides protection against traumatic brain injury-driven tauopathy pathogenesis
Year: 2025
Type: article
Abstract: snRNA-seq Phyton code for comparison of mild TBI PS19 mice to sham (non-injured controls) with and without VEGFC treatment. To asses gene expression differences between each of our four treatment groups (Sham+GFP, Sham+VEGFC, TBI+GFP, TBI+VEGFC) we combined the right (ipsilateral) hippocampus from 5 individual mice to yield a pooled sample of cells for each condition. The code includes files for both a global analysis of all the cells as well as a neuron specific reclustering.
Authors: Royo Marco, Ana, Bruch, Katherine R., Cowan, Maureen N., Dill, Julia G., Moore, Katelyn A., Bolte, Ashley C., Lukens, John R.
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7083426737
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