Effect of Cassia Occidentalis on Biochemical Parameters of Second-degree Burn Wounds in Wistar Strain Rats
Year: 2025
Type: article
Abstract: Cassia occidentalis, also known as false kinkeliba, is a medicinal plant known for its therapeutic properties. The objective of this study was to demonstrate its effects on certain biochemical parameters of wound healing in a model of second-degree experimental burns in Wistar rats. These burn wounds were treated with C. occidentalis leaf extract at doses of 125, 250, and 500 mg/kg, respectively, and concentrations of 40 and 80 mg/ml, and flukocin, a benchmark molecule for wound healing. The results of this work indicate certain pathways or mechanisms of pharmacological action that can support the healing effects of C. occidentalis. The 500 mg/kg extract promotes healing by reconstituting the skin layer. This healing process could be explained by the presence in the leaves of this plant of flavonoids, polyphenols, sterols and poly terpenes, alkaloids and saponosides contained in these leaves.
Author: Koudou Dago Désiré1,2*, Soro Silyibe1,2, Koffi Allali Eugène1,2, Gbogbo Moussa1,2, Okou Obou Constantin1,2
Language: English
Topic: Wound Healing and Treatments
Subfield: Rehabilitation
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7083589521
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