Features of psychopathological component of clinical profile of patients with atopic dermatitis
Year: 2025
Type: article
Abstract: Objective — to determine the features of the clinical profile and psychopathological symptoms in patients with atopic dermatitis, to assess the impact, taking into account the presence of pruriginous component as a potential factor that can affect the dynamics of the disease and the formation of psychoemotional disturbances. Materials and methods. This study was conducted on the basis of the Department of Dermatovenereology and Aesthetic Medicine of Zaporizhzhia State Medical and Pharmaceutical University. Verification of the diagnosis of atopic dermatitis was performed in 30 patients on the basis of clinical examination. The intensity of pruritus was assessed using a visual analog scale (VAS), rating parameters from 0 to 10, and the quality of life was assessed using a standardized questionnaire of the Dermatological Life Quality Index (DLQI). The profile of psychopathological symptoms was evaluated using the SCL90R symptom questionnaire. Results and discussion. The study included 21 (70 %) men aged 22 to 75 years (mean age (50.1 ± 4.0) years) and 9 (30 %) women aged 24 to 75 years (mean age (43.2 ± 6.1) years). In 23 (76.7 %) patients, atopic dermatitis had a classic course with the first appearance of eflorations in childhood and the corresponding official registration in medical records. At the same time, 11 (36.7 %) patients noted the course of dermatosis as chronic with alternating periods of remission and exacerbation throughout life. 12 (40 %) patients also had anamnestic data on atopy, but the period of remission was almost uninterrupted by exacerbations: the last episode in childhood and adolescence. In addition, 7 (23.3 %) patients with dermatosis after adulthood were examined, with categorical denial of efloriscence at any age. The average severity of itching was 4.9 ± 0.44, and the criterion of the maximum degree of intensity of this sensation was 7.0 ± 0.4. The dermatological quality of life index for the studied sample was 9 (7—12), which corresponds to moderate impact. A notable finding is the identified intragroup correlation between symptoms of the obsessivecompulsive spectrum and other psychopathological domains, highlighting the clinical significance of a comprehensive understanding of this component within the psychoemotional profile of patients with atopic dermatitis. Conclusions. The presence of the disease debut in adulthood indicates the diversity of the course of dermatitis and actualizes the need to focus on these phenotypic features at the stage of history taking and clinical examination. The definition of psychopathological symptoms for patients with atopic dermatitis complements the data on the clinical profile of these patients. Such an approach contributes to the formation of a comprehensive clinical assessment of the patient’s condition and justifies the feasibility of interdisciplinary management.
Authors: Н.І. Makurina, L.O. Horodokina
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7083671198
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