Evaluation of Analgesic Activity of Marine Sponge Tedania Anhelans
Year: 2025
Type: article
Abstract: In the present study, the methanolic extract of the marine sponge Tedania anhelans was evaluated for its phytochemical constituents and analgesic activity. Preliminary phytochemical screening revealed the presence of carbohydrates, steroids, terpenes and terpenoids. Acute toxicity studies indicated no mortality in rats at a dose of 5 g/kg body weight, suggesting a favourable safety profile. Analgesic activity was assessed using the tail immersion test in rats and the acetic acid-induced writhing test in mice, both of which demonstrated significant (p < 0.001) dose-dependent reductions in nociceptive responses. These findings suggest that Tedania anhelans possesses promising analgesic properties, supporting its potential as a source of bioactive compounds for therapeutic applications.
Author: Madiwalappa Ilkal1, Siddharam Bagalkote2, Akshay Kumar S. N.*3
Language: English
Subfield: Biotechnology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7083676613
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