Erythema Nodosum Revealing Silent Celiac Disease in Childhood: a Case Report
Year: 2025
Type: article
Abstract: Background: Erythema nodosum is the most frequent form of panniculitis, Its association with celiac disease remains uncommon, particularly in children. Case presentation: We report the case of a child presenting with recurrent erythema nodosum without gastrointestinal symptoms. Laboratory findings revealed severe iron deficiency despite prolonged oral supplementation. Serologic testing demonstrated elevated anti-transglutaminase IgA antibodies. Duodenal biopsy confirmed total villous atrophy with intraepithelial lymphocytosis confirming the diagnosis of coeiac disease. A gluten-free diet was introduced, leading to clinical and biological improvement. Conclusion: This case illustrates that celiac disease may present solely with extra-digestive manifestations such as erythema nodosum in children.
Author: S. Boujmil*a, N. Seghrouchnia, A. Laarajeb, A. Radib, S. Ait Hmaddoucha, A. Hassanib, R. Abilkassemb
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7083692576
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