Evaluation of Serum Cortisol Level in Chronic Superficial Dermatophytosis
Year: 2024
Type: article
Abstract: Introduction: The epidemic-like scenario of superficial fungal infections in India has been complicated by the rampant use of systemic and topical potent steroids. In this study, we hypothesize that the unjudicial use of topical corticosteroids can cause Hypothalamic pituitary axis suppression in chronic dermatophytosis patients. Objectives: To estimate morning serum cortisol levels in chronic superficial dermatophytosis patients. Materials and Methods: A total of 208 individuals were enrolled in this study. In which, 104 (50%) patients had Chronic superficial dermatophytosis (case group) and 104 (50%) patients were healthy (control group). Their clinical details and laboratory investigations including KOH and serum cortisol, were recorded on a pre-designed proforma. Results: The mean S. Cortisol level was 7.27±5.34 μg/ml in cases and 11.21±5.92 μg/ml in the control group. The mean S. Cortisol level was significantly lower in cases as than controls (p <0.001).Conclusion: This study shows that patients with chronic superficial dermatophytosis have low serum cortisol compared to healthy controls.
Authors: Varsha Dubey, Madhur Kant Rastogi, Nitin Mishra, Pratik Gahalaut, Amar Singh, Aaruj Dudea
Language: English
Topic: Nail Diseases and Treatments
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7084051563
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