Year: 2025
Type: article
Abstract: Hepatocerebral degeneration, also known as acquired hepatocerebral degeneration (AHD), is a rare neurological complication of chronic liver disease. It results from the accumulation of neurotoxic substances such as manganese and ammonia in the central nervous system, primarily affecting the basal ganglia. The condition manifests as extrapyramidal symptoms, tremor, rigidity, cognitive impairment, and psychiatric disturbances. This article presents a clinical case of a 52-year-old male with chronic liver cirrhosis who developed progressive neurological symptoms consistent with hepatocerebral degeneration. Diagnostic imaging, laboratory results, and therapeutic management are described. The report highlights the importance of early recognition and multidisciplinary treatment to prevent irreversible brain damage.
Authors: Muhammadzhon Bosimov, Komilzhon Boboniyazov
Institution: Tashkent State Medical University
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7086900110
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