Work

Selective Immunoglobulin Deficiency in Patients Treated with Lithium: Clinical and Immunological Insights

Year: 2025

Type: article

Abstract: Objective: To analyze the association between chronic lithium treatment and selective immunoglobulin deficiency, exploring pathophysiological mechanisms, clinical consequences, and monitoring strategies. Methods: Observational data from patients on long-term lithium therapy were combined with a review of the literature. Results: Lithium exposure was associated with reductions in immunoglobulin levels, particularly IgG and IgA, predisposing to recurrent infections and altered immune responses. Conclusion: Immunoglobulin deficiency should be considered an underrecognized complication of lithium therapy, requiring routine immunological monitoring and individualized management strategies.

Source: International Journal of Science and Research Archive

DOI: 10.5281/zenodo.17311822

Authors: Lozano, Roberto, Bona, Carina

Institutions: Hospital Clínico Universitario Lozano Blesa, Servicio Aragonés de Salud

Language: English

Topic: Immunodeficiency and Autoimmune Disorders

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W7087523154

FWCI:

Cites:

Cited by:

Related to: