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Prevalence of Folate Deficiency in Patients with Depressive Symptoms: Biochemical and Clinical Implications

Year: 2025

Type: article

Abstract: Objective: To evaluate the prevalence of folate deficiency in patients presenting with depressive symptoms and to explore associated biochemical abnormalities and clinical implications. Methods: Observational study analyzing serum folate, vitamin B12, ferritin, thyroid function, and homocysteine levels in patients with depressive symptoms. Results: Folate deficiency was prevalent in a significant subset of patients and was frequently associated with vitamin B12 deficiency, iron deficiency, and thyroid dysfunction. Conclusion: Folate deficiency is a common and potentially modifiable factor in depression, underscoring the need for routine biochemical screening in psychiatric care.

Source: International Journal of Science and Research Archive

DOI: 10.5281/zenodo.17311711

Authors: Lozano, Roberto, Bona, Carina

Institutions: Hospital Clínico Universitario Lozano Blesa, Servicio Aragonés de Salud

Language: English

Topic: Folate and B Vitamins Research

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W7087656574

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