Work

Rabies post exposure prophylaxis

Year: 2025

Type: article

Abstract: Animals are the source of 60% of known infectious diseases in humans and more than 75% of newly emerging infectious diseases. Among these zoonoses, rabies is of paramount public health concern because to its lethality. More than 99% of rabies-related deaths in India are caused by dog bites, making the disease a major cause of death in the nation, which requires Rabies Post Exposure Prophylaxis. Rabies post-exposure prophylaxis (PEP) prevents almost invariably fatal rabies infection after a bite, consisting of immediate wound care (soap and water, antiseptics), rabies vaccine, and, for severe exposures, rabies immunoglobulin (RIG) or monoclonal antibodies. While effective, access and adherence to PEP are major global challenges, highlighting the need for community education, improved access to affordable, and the importance of sustained canine rabies vaccination programs as the primary prevention strategy. Strict adherence to recommended schedules and protocols ensures maximum protection, reduces the risk of fatal infection, and supports the broader goal of rabies elimination in both humans and animals.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.17328466

Author: Narendra Kumar, Alok Mishra, Mayank Dubey, Vipin Maurya, Shailendra Chaurasia

Language: English

Topic: Rabies epidemiology and control

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7088193261

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