Work

Cover Feature: Inhibition of Lysosomal Cathepsin A and Neuraminidase 1 Interaction by Anti‐Obesity Cyclic Peptide (Chem. Eur. J. 56/2024)

Year: 2024
Type: article
Abstract: The Cover Feature highlights the docking model of lysosomal protective protein cathepsin A (PPCA) and the synthetic derivative of stylissatin A (SA), a cyclic heptapeptide from the Papua New Guinean marine sponge Stylissa sp. Focusing on this new-found protein–protein interaction inhibition mechanism of SA could lead to the development of new anti-obesity drugs. More information can be found in the Research Article by M. Kita and co-workers (DOI: 10.1002/chem.202402049).
Authors: Yiting Sun, Ayumi Dakiiwa, Menghua Zhang, Takahiro Shibata, Masaki Kita
Institution: Nagoya University
Language: English
Open Access status: bronze
OpenAlex ID: W7089691100
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