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Front Cover: Fluorocarbon‐DNA Conjugates for Enhanced Cellular Delivery: Formation of a Densely Packed DNA Nano‐Assembly (ChemBioChem 19/2024)

Year: 2024

Type: paratext

Abstract: Several RF-DNA conjugates are synthesized, and the relationship between the uptake efficiency and the physicochemical properties is systematically investigated. RF-DNA conjugates carrying two C8F17 groups at the terminus of a DNA strand form a nano-assembly with the highest DNA content, leading to the greatest cellular uptake via scavenger receptors. More details can be found in article 10.1002/cbic.202400436 by Ai Kohata, Kohsuke Aikawa, and co-workers.

Source: ChemBioChem

DOI: 10.1002/cbic.202481901

Authors: Minako Narita, Ai Kohata, Taiichi Kageyama, Honoka Watanabe, Kohsuke Aikawa, Daisuke Kawaguchi, Kunihiko Morihiro, Akimitsu Okamoto, Takashi Okazoe

Institutions: The University of Tokyo, Tokyo Institute of Technology, Asahi Glass (Japan)

Language: English

Topic: RNA Interference and Gene Delivery

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W7089715266

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