Alzheimer's Disease and the Mechanisms of Memory Loss
Year: 2025
Type: article
Abstract: Alzheimer’s disease AD is a chronic neurodegenerative condition characterized by progressive cognitive decline, particularly affecting memory. This disorder involves complex molecular and cellular changes in the brain, including the accumulation of amyloid-beta plaques, abnormal tau protein formations, loss of synaptic connections, oxidative stress, and inflammatory responses. These pathological events disrupt normal neuronal communication and contribute to the gradual deterioration of memory and other cognitive functions. Understanding the mechanisms behind memory impairment in AD is essential for developing new therapeutic approaches and improving patient care. This review summarizes current knowledge on the biological processes that lead to memory loss in Alzheimer’s disease and highlights potential targets for intervention.
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7091344244
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