Fatal Febrile Neutropenia in Post Chemotherapy Patient with Ovarian Dysgerminoma: A Case Report
Year: 2024
Type: article
Abstract: Introduction: Febrile Neutropenia (FN) is a condition characterized by fever and neutropenia, presents a critical concern in cancer treatment, particularly in ovarian cancer patients receiving chemotherapy. The incidence of FN is influenced by various factors, including chemotherapy regimen, patient demographics, and overall health status.Case Presentation: A 20-year-old woman presented with abdominal distension, pain, and weight loss, indicative of advanced intra-abdominal pathology. Surgical exploration revealed extensive disease, prompting suboptimal tumor debulking and total abdominal hysterectomy with bilateral salpingo-oophorectomy. Postoperatively, the patient was at high risk for FN, necessitating vigilant monitoring and prompt intervention.Discussion: FN in ovarian cancer patients underscores the complexity of treatment, as chemotherapy-induced neutropenia significantly increases infection susceptibility. Prophylactic measures, including granulocyte colony-stimulating factors (G-CSFs) and antimicrobial therapy, play a crucial role in reducing FN incidence and severity. Early detection and prompt antibiotic initiation are essential in managing FN effectively.Conclusion: The case report highlights the challenges of managing ovarian cancer and the importance of proactive FN management. By prioritizing personalized care and early intervention, healthcare providers can optimize outcomes and enhance patient quality of life.
Source: Jurnal Kedokteran Syiah Kuala
Author: Munizar Munizar
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7092290303
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