Work

When Supplements Turn Dangerous: Glucocorticoid-Induced Adrenal Insufficiency From Hidden Steroids

Year: 2025

Type: article

Abstract: We report a case of glucocorticoid-induced adrenal insufficiency following the use of 3 different herbal supplements containing hidden steroids. The patient presented with nonspecific symptoms, including fatigue and gastrointestinal upset, complicating diagnosis. These supplements contributed to life-threatening infections and hemorrhagic shock from an upper gastrointestinal bleed. This case emphasizes the clinical challenges and health risks associated with the use of unregulated supplements. Many patients consider these supplements safe; however, they may contain ingredients that pose serious health threats. Increased awareness, comprehensive history, and careful diagnostic approaches are crucial in effectively managing such cases.

Source: Annals of Internal Medicine Clinical Cases

DOI: 10.7326/aimcc.2024.1203

Authors: Aye Khine, Ahmed Najar, Sophie Patzek

Institution: University of California, San Francisco

Language: English

Topic: Adrenal Hormones and Disorders

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: National Institutes of Health