Étude histologique de nothobranchius furzeri : un nouveau modèle animal dans l’étude du vieillissement comparé
Year: 2023
Type: dissertation
Abstract: Nothobranchius furzeri is a new animal model in aging studies. This fish histology, that is neither very well known nor described, represents a relevant approach for this kind of study. The first, bibliographic, part of the thesis presents the model and justifies its use in aging studies. The second, experimental part has been completed with team 2 of RESTORE institute that gave all the fishes used in the study. Histological slides were created for the two genders and for different age, between 1 and 8 months, individuals. The slides are scanned and annotated on the Cytomine web-based platform. The ambition of this manuscript is to describe the organs and tissues histology in order to create an histological atlas of Nothobranchius that could be considered as a reference work for researches using this model. This atlas, on digital slides, should be accessible for consultation for scientific community. This work takes part of the INSPIRE project which is driven in Occitanie since 2019. The main objective is to identify histological and biological markers of aging.
Source: HAL
Author: Lepori, Manon
Language: French
Subfield: Aging
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7094231912