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Analytical Method Using Nbsa Reagent for Quantification of Pure and Pharmaceutical Antihistamine Drugs

Year: 2025

Type: article

Abstract: A quick and convenient method has been developed for the micro estimation of antihistamine drugs. 1-5 mg of sample is allowed to react with 10 ml of 0.02 M, N-bromosaccharin solution. Unconsumed reagent can be accurately titrated with 5 ml of 15% KI and 0.02N sodium thiosulphate solution using starch as indicator. SD and CV was calculated for reproducible and accurate result. The accuracy of the method is within + 1 % and possible course of reaction was suggested on the basis of stoichiometry as well as find reaction product.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.17433173

Author: Meera, Prasad Verma

Language: English

Topic: Analytical Methods in Pharmaceuticals

Subfield: Analytical Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W7094953889

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