Comment on: Besser et al. Lessons From the Mixed-Meal Tolerance Test: Use of 90-Minute and Fasting C-Peptide in Pediatric Diabetes. Diabetes Care 2013;36:195–201
Year: 2013
Type: letter
Abstract: I t was extremely gratifying to read aninteresting article in Diabetes Care byBesser et al. (1) that suggested that 90-min C-peptide is a highly sensitive and specific measure of area under curve and peak C-peptide in children and ado-lescents with type 1 diabetes and offers a practical alternative to a full mixed-meal tolerance test. The authors also suggested that C-peptide measured at diagnosis and age at diagnosis can be used to predict the time taken for patients to become insulin-deficient. The authors suggested that those with the lowest tertile of fasting C-peptide (,0.17 nmol/L) reached insulin defi-ciency quicker than those in the highest tertile of fasting C-peptide ($0.29 nmol/L)
Source: Diabetes Care
DOI: 10.2337/dc13-0369
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W2102282743