Work

Modeling ripple oscillations in the hippocampus

Year: 2013
Type: article
Abstract: Sharp wave-ripples (SWRs) are highly synchronous net-work events displayed by the mammalian hippocampus during slow-wave sleep and immobile resting periods. A SWR event (~100 ms duration) is characterized by fast network oscillations (~200 Hz “ripples”) superimposed by a sharp wave, which is a large-amplitude, low-fre-quency (<10 Hz) signature in the local field potential of the hippocampal CA1 region. Such events are involved in memory consolidation. Understanding the mechan-isms that give rise to SWRs can help us to gain insights on the computations being implemented during memory consolidation. Despite a large amount of electrophysiological data on SWRs in vivo (e.g. [1]) and in vitro (e.g. [2-4]) and many computational models (e.g. [5] and [6]), the basic
Language: English
Open Access status: gold
Estimated APC paid: $2,990
OpenAlex ID: W1780411489
FWCI: 0.155
Cites: 7
Cited by: 1
Related to: 10