Ageing or NOT, clock genes are important for memory processes: an interesting hypothesis raising many questions
Year: 2010
Type: article
Abstract: Memory processes, such as acquisition, consolidation and retrieval are temporally regulated events. An intrinsic circadian (circa: about; dies: day) timing system influencing the dynamics in memory processing has been detected in animal models, ranging from invertebrates to mammalian species. Several recent investigations, addressing the molecular mechanism behind the circadian modulation of mnemonic processes shed light onto pathways known to be essential in memory processing, such as the cAMP-CREB-MAPKpathway, which by itself is regulated by the circadian system. Notable, an important role for rhythmic clock gene expressions in the hippocampus and in hippocampus-dependent memory processes has been recently detected. However, the link between the
Source: Aging
Authors: Oliver Rawashdeh, Jörg H. Stehle
Language: English
Subfield: Endocrine and Autonomic Systems
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W1225534