Work

Therapeutic options and challenges for substances of abuse

Year: 2007

Type: article

Abstract: Addiction to substances continues to be a significant public health concern in the United States. The following review of current pharmacological treatments discusses a range of substances: nicotine, alcohol, cocaine, and opioids. The goal is to provide an overview of currently available and new pharmacological treatments for substance use disorders, while also addressing the pharmacotherapeutic challenges remaining. The significant advances in pharmacotherapy have had limited utilization, however. For example, naltrexone for alcoholism is infrequently prescribed, buprenorphine for opiates still has relatively few qualified prescribers, and stimulants have no Food and Drug Administration-approved pharmacotherapy. These pharmacotherapies are needed, with the rate of even the relatively uncommon abuse of opiates now rising sharply.

Source: Dialogues in Clinical Neuroscience

DOI: 10.31887/dcns.2007.9.4/tgardner

Authors: Tracie J. Gardner, Thomas R. Kosten

Institutions: Michael E. DeBakey VA Medical Center, Baylor College of Medicine

Language: English

Topic: Substance Abuse Treatment and Outcomes

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4213461946

FWCI: 1.217

Cites: 167

Cited by: 13

Related to: 10