Work

Alginate microparticles for biodelivery: A review

Year: 2011

Type: article

Abstract: Transplantation of microencapsulated cells, proteins and bacteria has been proposed as a therapy for a broad variety of diseases as it permits for transplantation by immunoisolation, that is, without unwanted immunosuppression. The immunoisolation technology protects foreign cells against the host immune system by a synthetic film (coat). Microencapsulation offers a mode to enclose bioactive substances within a polymeric covering for biomedical applications. The present article, offers a review of microencapsulation for the rationale of shielding the bioactive substances and releasing the enclosed substances in a controlled manner. It encompasses the chemistry of alginate and describes the properties and biomedical applications of alginate-based microparticles.

Source: African Journal of Pharmacy and Pharmacology

DOI: 10.5897/ajpp11.706

Author: Ghulam Murtaza,

Language: English

Topic: Advanced Drug Delivery Systems

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2163904143

FWCI: 0.857

Cites: 63

Cited by: 13

Related to: 10