Work

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

Year: 2014

Type: article

Source: Nature Biotechnology

DOI: 10.1038/nbt.2808

Authors: Yanfang Fu, Jeffry D Sander, Deepak Reyon, Vincent M Cascio, J Keith Joung

Institutions: Harvard University, Massachusetts General Hospital, Center for Computational and Integrative Biology, Massachusetts General Hospital

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: Massachusetts General Hospital, National Institutes of Health, National Human Genome Research Institute, National Institute of General Medical Sciences, Army Research Office, Army Research Laboratory

Awards: Causal Transcriptional Consequences of Human Genetic Variation, Advancing stem cell technologies using engineered zinc finger proteins, G5259331294, G6781161026, ADVANCING GENE-EDITING NUCLEASES FOR TARGETED GENOME MANIPULATION, G7452299184, G862988727

OpenAlex ID: W2108038398

FWCI: 83.78

Cites: 30

Cited by: 1,977

Related to: 10